National trends of acute kidney injury requiring dialysis in decompensated cirrhosis hospitalizations in the United States
| Autor: | Achint Patel, Shanti Patel, Chirag R. Parikh, Ioannis Konstantinidis, Girish N. Nadkarni, Narender Annapureddy, Rabi Yacoub, Sunil Kamat, Priya K. Simoes, Steven G. Coca |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty medicine.medical_treatment 030232 urology & nephrology urologic and male genital diseases Single Center Logistic regression 03 medical and health sciences Young Adult 0302 clinical medicine Renal Dialysis Medicine Humans Young adult Intensive care medicine Dialysis Aged Hepatology business.industry Incidence (epidemiology) Incidence Acute kidney injury Odds ratio Acute Kidney Injury Middle Aged medicine.disease female genital diseases and pregnancy complications United States Hospitalization Emergency medicine Cohort 030211 gastroenterology & hepatology Female business |
| Zdroj: | Hepatology international. 10(3) |
| ISSN: | 1936-0541 |
| Popis: | Cirrhosis affects 5.5 million patients with estimated costs of US$4 billion. Previous studies about dialysis requiring acute kidney injury (AKI-D) in decompensated cirrhosis (DC) are from a single center/year. We aimed to describe national trends of incidence and impact of AKI-D in DC hospitalizations. We extracted our cohort from the Nationwide Inpatient Sample (NIS) from 2006–2012. We identified hospitalizations with DC and AKI-D by validated ICD9 codes. We analyzed temporal changes in DC hospitalizations complicated by AKI-D and utilized multivariable logistic regression models to estimate AKI-D impact on hospital mortality. We identified a total of 3,655,700 adult DC hospitalizations from 2006 to 2012 of which 78,015 (2.1 %) had AKI-D. The proportion with AKI-D increased from 1.5 % in 2006 to 2.23 % in 2012; it was stable between 2009 and 2012 despite an increase in absolute numbers from 6773 to 13,930. The overall hospital mortality was significantly higher in hospitalizations with AKI-D versus those without (40.87 vs. 6.96 %; p |
| Databáze: | OpenAIRE |
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