Identification of BCR-ABL Fusion on Chromosome 9 by Fluorescence In Situ Hybridization in Two Chronic Myeloid Leukemia Cases

Autor:	Robert G. Watts, Kelly Cox, Andrew J. Carroll, P. Nagesh Rao, Bethy Jackle, Elizabetta Abruzzese, Mary C. Steuterman, Mark J. Pettenati
Rok vydání:	1998
Předmět:	Male Cancer Research Adolescent Fusion Proteins bcr-abl Chromosome 9 Chromosomal translocation Biology Philadelphia chromosome Leukemia Myelogenous Chronic BCR-ABL Positive hemic and lymphatic diseases Genetics medicine Humans Philadelphia Chromosome Molecular Biology In Situ Hybridization Fluorescence ABL medicine.diagnostic_test breakpoint cluster region Myeloid leukemia Gene rearrangement Middle Aged medicine.disease Cancer research Female Chromosomes Human Pair 9 Fluorescence in situ hybridization
Zdroj:	Cancer Genetics and Cytogenetics. 105:164-167
ISSN:	0165-4608
Popis:	We present two cases with hidden Philadelphia translocations that resulted from an insertion and a complex translocation. These cases were unusual in having the BCR/ABL fusion localized to chromosome 9q34. A review of cases with these uncommon presentations of BCR/ABL and prognostic presentation is presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32df8120d47fb9e275362d3a0833d10c https://doi.org/10.1016/s0165-4608(98)00020-x Zobrazit plný text záznamu Full Text from ScienceDirect