Peripheral Nerve Ultrasound in Small Fiber Polyneuropathy
| Autor: | Vera Bril, Ari Breiner, Mylan Ngo, Hafsah Siddiqui, Hamid Ebadi, Sepehr Ebadi |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Acoustics and Ultrasonics Biophysics Urology Nerve fiber Sural nerve Polyneuropathies Nerve Fibers medicine Humans Radiology Nuclear Medicine and imaging Peripheral Nerves Fiber Ultrasonography Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Ultrasound Reproducibility of Results Echogenicity Middle Aged medicine.disease Surgery medicine.anatomical_structure Skin biopsy Female business Body mass index Polyneuropathy |
| Zdroj: | Ultrasound in Medicine & Biology. 41:2820-2826 |
| ISSN: | 0301-5629 |
| DOI: | 10.1016/j.ultrasmedbio.2015.06.011 |
| Popis: | Routine nerve conduction studies are normal in patients with small fiber neuropathy (SFN), and a definitive diagnosis is based on skin biopsy revealing reduced intra-epidermal nerve fiber density (IENFD). In large fiber polyneuropathy, ultrasound (US) parameters indicate enlargement in cross-sectional area (CSA). This study was aimed at determining if similar changes in large fibers on US are apparent in patients with SFN. Twenty-five patients with SFN diagnosed by reduced IENFD and 25 age- and body mass index (BMI)-matched healthy controls underwent US studies of sural and superficial peroneal sensory nerves. The mean CSA of the sural nerve in SFN patients was 3.2 ± 0.8 mm(2), and in controls, 2.7 ± 0.6 mm(2) (p < 0.0070), and this was independent of sex. There was no difference in the thickness-to-width ratio or echogenicity of the nerves. US of the sural nerve in patients diagnosed with small fiber neuropathy reveals an enlarged cross-sectional area similar to that in large fiber polyneuropathy. |
| Databáze: | OpenAIRE |
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