18F-FDG uptake in the stomach on screening PET/CT: value for predicting Helicobacter pylori infection and chronic atrophic gastritis

Autor: Masaki Katsurahara, Shigeki Kobayashi, Naohisa Suzawa, Hajime Sakuma, Mayumi Ogura, Toru Ogura, Noriyuki Horiki
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: BMC Medical Imaging
ISSN: 1471-2342
Popis: Background The aim of this study was to determine the value of 18F-FDG uptake on screening PET/CT images for the prediction of Helicobacter pylori (H. pylori) infection and chronic atrophic gastritis. Methods Among subjects who underwent 18F-FDG PET/CT for cancer screening from April 2005 to November 2015, PET/CT images were analyzed in 88 subjects who had gastrointestinal fiberscopy within 6 months. The volumes of interest (VOIs) were placed in the fornix, corpus and antrum of the stomach to determine maximal standardized uptake value (SUVmax) and mean SUV (SUVmean). Receiver operating characteristic curve (ROC) analysis was performed to determine the diagnostic performance of SUV indicators in predicting H. pylori infection and chronic atrophic gastritis. Results SUV indicators of the stomach were significantly higher in subjects with H. pylori infection than those without (from P
Databáze: OpenAIRE