PCR diagnosis of tick-borne pathogens in Maharashtra state, India indicates fitness cost associated with carrier infections is greater for crossbreed than native cattle breeds
| Autor: | S. W. Kolte, Stephen D. Larcombe, Ganesh Warthi, Swapnil P. Magar, Elizabeth Glass, Nitin V. Kurkure, Brian Shiels, Suresh Gulabrao Jadhao |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Veterinary medicine Rickettsiales lcsh:Medicine Pathogenesis Cattle Diseases Pathology and Laboratory Medicine Polymerase Chain Reaction Tropical theileriosis Geographical Locations 0403 veterinary science Ticks Medicine and Health Sciences lcsh:Science Pathogen Subclinical infection Mammals 2. Zero hunger Tick-borne disease Multidisciplinary biology Transmission (medicine) Agriculture Ruminants 04 agricultural and veterinary sciences 030108 mycology & parasitology Bacterial Pathogens Veterinary Diseases Tick-Borne Diseases Medical Microbiology Vertebrates Host-Pathogen Interactions Pathogens Research Article Livestock Anaplasma Asia 040301 veterinary sciences India Microbiology Crossbreed 03 medical and health sciences Bovines Parasite Groups Parasitic Diseases medicine Animals Microbial Pathogens Bacteria lcsh:R Organisms Biology and Life Sciences biology.organism_classification medicine.disease Theileria annulata Theileriasis Amniotes People and Places Cattle Veterinary Science Parasitology lcsh:Q Apicomplexa |
| Zdroj: | PLoS ONE, Vol 12, Iss 3, p e0174595 (2017) PLoS ONE Kolte, S W, Larcombe, S D, Jadhao, S G, Magar, S P, Warthi, G, Kurkure, N V, Glass, E J & Shiels, B R 2017, ' PCR diagnosis of tick-borne pathogens in Maharashtra state, India indicates fitness cost associated with carrier infections is greater for crossbreed than native cattle breeds ', PLoS ONE, vol. 12, no. 3, e0174595 . https://doi.org/10.1371/journal.pone.0174595 |
| ISSN: | 1932-6203 |
| Popis: | Tick-borne pathogens (TBP) are responsible for significant economic losses to cattle production, globally. This is particularly true in countries like India where TBP constrain rearing of high yielding Bos taurus, as they show susceptibility to acute tick borne disease (TBD), most notably tropical theileriosis caused by Theileria annulata. This has led to a programme of cross breeding Bos taurus (Holstein-Friesian or Jersey) with native Bos indicus (numerous) breeds to generate cattle that are more resistant to disease. However, the cost to fitness of subclinical carrier infection in crossbreeds relative to native breeds is unknown, but could represent a significant hidden economic cost. In this study, a total of 1052 bovine blood samples, together with associated data on host type, sex and body score, were collected from apparently healthy animals in four different agro-climatic zones of Maharashtra state. Samples were screened by PCR for detection of five major TBPs: T. annulata, T. orientalis, B. bigemina, B. bovis and Anaplasma spp.. The results demonstrated that single and co-infection with TBP are common, and although differences in pathogen spp. prevalence across the climatic zones were detected, simplistic regression models predicted that host type, sex and location are all likely to impact on prevalence of TBP. In order to remove issues with autocorrelation between variables, a subset of the dataset was modelled to assess any impact of TBP infection on body score of crossbreed versus native breed cattle (breed type). The model showed significant association between infection with TBP (particularly apicomplexan parasites) and poorer body condition for crossbreed animals. These findings indicate potential cost of TBP carrier infection on crossbreed productivity. Thus, there is a case for development of strategies for targeted breeding to combine productivity traits with disease resistance, or to prevent transmission of TBP in India for economic benefit. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|