Rates of Ipsilateral Local-regional Recurrence in High-risk Patients Undergoing Immediate Post-mastectomy Reconstruction (AFT-01)
| Autor: | Jessica R. Schumacher, Alyssa A. Wiener, Samuel O. Poore, Caprice C. Greenberg, Amanda B. Francescatti, Christina M. Dudley, Heather B. Neuman, Trista J. Stankowski-Drengler |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Adult Cancer Research medicine.medical_specialty medicine.medical_treatment Breast Neoplasms Cancer recurrence Disease-Free Survival Article 03 medical and health sciences 0302 clinical medicine Breast cancer Post mastectomy Risk Factors medicine Humans Mastectomy High risk patients business.industry Proportional hazards model Cancer Middle Aged medicine.disease Surgery 030104 developmental biology Oncology 030220 oncology & carcinogenesis Female Neoplasm Recurrence Local business Breast reconstruction Follow-Up Studies |
| Zdroj: | Clin Breast Cancer |
| ISSN: | 1938-0666 |
| Popis: | BACKGROUND AND OBJECTIVES: Some surgeons remain hesitant to perform immediate breast reconstruction (IBR) in patients with higher risk cancers due to concerns about cancer recurrence and/or detection. Our objective was to determine the rate of ipsilateral local-regional recurrence for stage II/III patients who underwent IBR. METHODS: The National Cancer Database special study mechanism was used to create a stratified sample of women diagnosed with stage II/III breast cancer from 1,217 facilities. Demographic, tumor, and recurrence data for women who underwent mastectomy with or without IBR were abstracted, including location of recurrence and method of detection. Estimates of 5-year local-regional recurrence rates were calculated and factors associated with recurrence were identified with multivariable Cox regression. RESULTS: 13% (692/5,318) of stage II/III patients underwent IBR after mastectomy. Patients undergoing IBR were younger (p |
| Databáze: | OpenAIRE |
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