Clinical Outcomes of Biliary Drainage during a Neoadjuvant Therapy for Pancreatic Cancer: Metal versus Plastic Stents
| Autor: | Toru Nakamura, Tsuyoshi Hayashi, Masayo Motoya, Koji Imai, Keisuke Yamakita, Michihiro Ono, Satoshi Hirano, Takuma Goto, Yasutoshi Kimura, Kuniyuki Takahashi, Masaki Kuwatani, Hiroyuki Maguchi |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Pancreatic neoplasms medicine.medical_treatment Jaundice Brief Communication Gastroenterology 03 medical and health sciences 0302 clinical medicine Postoperative Complications Recurrence Internal medicine Pancreatic cancer Stent Medicine Humans Chemotherapy Neoadjuvant therapy Aged Retrospective Studies Cholestasis Hepatology business.industry Perioperative Equipment Design Chemoradiotherapy Middle Aged medicine.disease Neoadjuvant Therapy Discontinuation Treatment Outcome Metals 030220 oncology & carcinogenesis Drainage 030211 gastroenterology & hepatology Female Stents medicine.symptom business Plastics |
| Zdroj: | Gut and Liver |
| ISSN: | 2005-1212 |
| Popis: | Neoadjuvant chemotherapy/neoadjuvant chemoradiotherapy (NAC/NACRT) can be performed in patients with pancreatic cancer to improve survival. We aimed to clarify the clinical outcomes of biliary drainage with a metal stent (MS) or a plastic stent (PS) during NAC/NACRT. Between October 2013 and April 2016, 96 patients with pancreatic cancer were registered for NAC/NACRT. Of these, 29 patients who underwent biliary drainage with MS or PS before NAC/NACRT and a subsequent pancreatoduodenectomy were retrospectively analyzed with regard to patient characteristics, preoperative recurrent biliary obstruction rate, NAC/NACRT delay or discontinuation rate, and operative characteristics. The median age of the patients was 67 years. NAC and NACRT were performed in 14 and 15 patients, respectively, and MS and PS were used in 17 and 12 patients, respectively. Recurrent biliary obstruction occurred in 6% and 83% of the patients in the MS and PS groups, respectively (p |
| Databáze: | OpenAIRE |
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