From Enzyme Stability to Enzymatic Bioelectrode Stabilization Processes
| Autor: | Anne de Poulpiquet, Ievgen Mazurenko, Hiu-Mun Man, Charlène Beaufils, Elisabeth Lojou |
|---|---|
| Přispěvatelé: | Bioénergétique et Ingénierie des Protéines (BIP ), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Région PACAHyseas companyAgence Innovation Defense, ANR-16-CE05-0024,Enzymor,Bases moléculaires de l'immobilisation fonctionnelle d'enzymes pour des biopiles performantes(2016) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
[SDV.BIO]Life Sciences [q-bio]/Biotechnology Metalloenzyme Nanotechnology 02 engineering and technology lcsh:Chemical technology 010402 general chemistry 01 natural sciences Catalysis lcsh:Chemistry Bioelectrochemistry Redox enzymes medicine Electrochemistry lcsh:TP1-1185 Physical and Theoretical Chemistry chemistry.chemical_classification Chemistry Scale development Protein engineering [CHIM.CATA]Chemical Sciences/Catalysis 021001 nanoscience & nanotechnology 0104 chemical sciences Enzyme lcsh:QD1-999 0210 nano-technology [CHIM.OTHE]Chemical Sciences/Other Biosensor Stability |
| Zdroj: | Catalysts Catalysts, MDPI, 2021, 11 (4), pp.497. ⟨10.3390/catal11040497⟩ Catalysts, Vol 11, Iss 497, p 497 (2021) Catalysts, 2021, 11 (4), pp.497. ⟨10.3390/catal11040497⟩ |
| ISSN: | 2073-4344 |
| DOI: | 10.3390/catal11040497⟩ |
| Popis: | International audience; Bioelectrocatalysis using redox enzymes appears as a sustainable way for biosensing, electricity production, or biosynthesis of fine products. Despite advances in the knowledge of parameters that drive the efficiency of enzymatic electrocatalysis, the weak stability of bioelectrodes prevents large scale development of bioelectrocatalysis. In this review, starting from the understanding of the parameters that drive protein instability, we will discuss the main strategies available to improve all enzyme stability, including use of chemicals, protein engineering and immobilization. Considering in a second step the additional requirements for use of redox enzymes, we will evaluate how far these general strategies can be applied to bioelectrocatalysis. |
| Databáze: | OpenAIRE |
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