Does exogenous androgen use affect the retinal blood flow: An OCTA study in transgender men
| Autor: | Nevin Tüten, Busenur Gonen, Abdullah Tuten, Kubra Hamzaoglu, Didar Ucar |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Retinal blood flow medicine.drug_class 030209 endocrinology & metabolism Transgender Persons 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Vessel density Ophthalmology Transgender Humans Medicine Fluorescein Angiography business.industry Retinal Vessels Retinal General Medicine Foveal avascular zone Optical coherence tomography angiography Androgen medicine.anatomical_structure chemistry Androgens 030221 ophthalmology & optometry Female business Tomography Optical Coherence Optic disc |
| Zdroj: | European Journal of Ophthalmology. 32:1570-1576 |
| ISSN: | 1724-6016 1120-6721 |
| DOI: | 10.1177/11206721211020639 |
| Popis: | Purpose: This study aims to investigate the effect of using exogenous androgen on retinal microvascular structures in transgender men. Methods: Retinal microvascular structures of transgender men and healthy women in the control group were visualized with optical coherence tomography angiography (OCTA). Foveal avascular zone (FAZ), superficial capillary vascular density (sCVD), deep capillary vascular density (dCVD), and radial peripapillary capillary (RPC) vascular density were evaluated. Results: Thirty transgender men and 30 healthy women were included in the study. There were no significant differences between transgender men and the control group in terms of FAZ, central macular thickness, parafoveal, and perifoveal retinal thicknesses ( p = 0.859, 0.288, 0.561, and 0.719; respectively). sCVD were found to be low in transgender men in the whole image, parafoveal, and perifoveal zones ( p = 0.006, 0.025, and 0.005; respectively). Although there were low values of dCVD of the whole image, parafoveal, and perifoveal zones in transgender men, the difference was not statistically significant ( p = 0.295, 0.085, and 0.270; respectively). RPC vessel densities in the whole image, peripapillary zone, and the inferior of the optic disc were found to be significantly low in transgender men ( p = 0.003, 0.005, and 0.003; respectively). Conclusion: In this study, a decrease in vessel density in the superficial retinal layers and around the optic disc was detected in transgender men. These findings suggest that routine ophthalmological examination may be important in individuals who use exogenous androgens. |
| Databáze: | OpenAIRE |
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