Contribution of the Retrovirus Epidemiology Donor Study (REDS) to research on blood transfusion safety in Brazil
| Autor: | Nanci A. Salles, João Eduardo Ferreira, Paula Fraiman Blatyta, Melissa King, Paula Loureiro, Thelma T. Gonçalez, Giuseppina M. Patavino, Ligia Capuani, Divaldo Sampaio, Cláudia Di Lorenzo Oliveira, Cesar de Almeida-Neto, Maria Esther Lopes, Maria Inês Lopes, Edward L. Murphy, Ester Cerdeira Sabino, Anna Bárbara de Freitas Carneiro Proietti, Silvana Leão, Michael P. Busch, Alfredo Mendrone-Junior, Brian Custer |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Blood transfusion medicine.medical_treatment Blood-borne infectious diseases Context (language use) Transfusion safety Update article Acquired immunodeficiency syndrome (AIDS) Epidemiology medicine 2.2 Factors relating to the physical environment Aetiology Deferral Blood donation lcsh:RC633-647.5 business.industry Transmission (medicine) Prevention Transfusion medicine lcsh:Diseases of the blood and blood-forming organs Hematology medicine.disease Residual risk Infectious Diseases Good Health and Well Being Cardiovascular System & Hematology Family medicine Immunology HIV/AIDS Patient Safety Infection business 2.4 Surveillance and distribution |
| Zdroj: | Revista Brasileira de Hematologia e Hemoterapia, Volume: 36, Issue: 2, Pages: 152-158, Published: APR 2014 Revista Brasileira de Hematologia e Hemoterapia v.36 n.2 2014 Revista brasileira de hematologia e hemoterapia Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) instacron:ABHHTC Revista brasileira de hematologia e hemoterapia, vol 36, iss 2 Revista Brasileira de Hematologia e Hemoterapia, Vol 36, Iss 2, Pp 152-158 (2014) Revista Brasileira de Hematologia e Hemoterapia Loureiro, P; De Almeida-Neto, C; Proietti, ABC; Capuani, L; Gonçalez, TT; De Oliveira, CDL; et al.(2014). Contribution of the Retrovirus Epidemiology Donor Study (REDS) to research on blood transfusion safety in Brazil. Revista Brasileira de Hematologia e Hemoterapia, 36(2), 152-158. doi: 10.5581/1516-8484.20140033. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3sd7t97j |
| DOI: | 10.5581/1516-8484.20140033. |
| Popis: | The Retrovirus Epidemiology Donor Study (REDS) program was established in the United States in 1989 with the purpose of increasing blood transfusion safety in the context of the HIV/AIDS and human T-lymphotropic virus epidemics. REDS and its successor, REDS-II were at first conducted in the US, then expanded in 2006 to include international partnerships with Brazil and China. In 2011, a third wave of REDS renamed the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) was launched. This seven-year research program focuses on both blood banking and transfusion medicine research in the United States of America, Brazil, China, and South Africa. The main goal of the international programs is to reduce and prevent the transmission of HIV/AIDS and other known and emerging infectious agents through transfusion, and to address research questions aimed at understanding global issues related to the availability of safe blood. This article describes the contribution of REDS-II to transfusion safety in Brazil. Articles published from 2010 to 2013 are summarized, including database analyses to characterize blood donors, deferral rates, and prevalence, incidence and residual risk of the main blood-borne infections. Specific studies were developed to understand donor motivation, the impact of the deferral questions, risk factors and molecular surveillance among HIV-positive donors, and the natural history of Chagas disease. The purpose of this review is to disseminate the acquired knowledge and briefly summarize the findings of the REDS-II studies conducted in Brazil as well as to introduce the scope of the REDS-III program that is now in progress and will continue through 2018.© 2014 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. All rights reserved. |
| Databáze: | OpenAIRE |
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