Polyunsaturated fatty acids in maternal plasma and in breast milk

Autor: Marcello Giovannini, Francesco Marangoni, Carlo Agostoni, Corrado L. Galli, A.M. Lammardo, Elisabetta Riva, Milena Bonvissuto
Rok vydání: 2002
Předmět:
Zdroj: Prostaglandins, leukotrienes, and essential fatty acids. 66(5-6)
ISSN: 0952-3278
Popis: Summary In order to explain processes underlying the transfer of fatty acids from the maternal compartment into human milk, the lipid content and the fatty acid composition of maternal plasma and milk have been analyzed in breastfeeding mothers at1day and 3 months of lactation. The rise in milk lipids occurring during the study period was concomitant with a fall in plasma total fat content, mainly due to the decrease of triglycerides. Significant correlations between plasma and milk fatty acids at the two time points were observed only for linoleic (LA,18:2 n-6) and (a-linolenic acid (aLNA,18:3 n-3), while for arachidonic (AA, 20:4 n-6) and docosahexaenoic acid (DHA, 22:6 n-3) correlations were found only at one day and 3 months, respectively. These data suggest that levels of the n-6 and n-318C polyunsaturated fatty acidsin milk are closely dependent on their concentrations in maternal plasma, in turn related with the dietary intake, while the accumulation of AA and DHA in milk is the result of a sequence of transfer and metabolic processes. & 2002 Elsevier Science Ltd. All rights reserved.
Databáze: OpenAIRE