Improvement of cardiovascular risk prediction: time to review current knowledge, debates, and fundamentals on how to assess test characteristics
| Autor: | Georg Noll, Michel Romanens, Nicolas Rodondi, Franz Ackermann, Roger Darioli, Matthias Schwenkglenks, Roberto Corti, John David Spence, Michael J. Pencina |
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| Přispěvatelé: | University of Zurich, Romanens, M |
| Rok vydání: | 2010 |
| Předmět: |
Carotid Artery Diseases
Epidemiology Cost-Benefit Analysis 610 Medicine & health Vascular risk Risk Assessment 2705 Cardiology and Cardiovascular Medicine Predictive Value of Tests Risk Factors Statistics Odds Ratio Health Status Indicators Humans Medicine Dyslipidemias Likelihood Functions Evidence-Based Medicine Models Statistical Actuarial science business.industry Cholesterol HDL Discriminant Analysis Reproducibility of Results 10060 Epidemiology Biostatistics and Prevention Institute (EBPI) Odds ratio Prognosis Test (assessment) ROC Curve Work (electrical) Atherosclerosis imaging Cardiovascular Diseases Relative risk Practice Guidelines as Topic 10209 Clinic for Cardiology Clinical value Cardiology and Cardiovascular Medicine business Risk assessment Biomarkers 2713 Epidemiology |
| Zdroj: | European Journal of Cardiovascular Prevention & Rehabilitation. 17:18-23 |
| ISSN: | 1741-8267 |
| Popis: | Cardiovascular risk assessment might be improved with the addition of emerging, new tests derived from atherosclerosis imaging, laboratory tests or functional tests. This article reviews relative risk, odds ratios, receiver-operating curves, posttest risk calculations based on likelihood ratios, the net reclassification improvement and integrated discrimination. This serves to determine whether a new test has an added clinical value on top of conventional risk testing and how this can be verified statistically. Two clinically meaningful examples serve to illustrate novel approaches. This work serves as a review and basic work for the development of new guidelines on cardiovascular risk prediction, taking into account emerging tests, to be proposed by members of the 'Taskforce on Vascular Risk Prediction' under the auspices of the Working Group 'Swiss Atherosclerosis' of the Swiss Society of Cardiology in the future. |
| Databáze: | OpenAIRE |
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