Unexpected rapid increase in bone mineral density by bisphosphonate therapy after multiple spinal fractures: a case report
| Autor: | Mikio Kamimura, Hidefumi Koiwai, Yukio Nakamura, Hiroyuki Kato, Jun Takahashi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Osteoporosis Urology lcsh:Medicine 030209 endocrinology & metabolism Case Report Bone healing Collagen Type I 03 medical and health sciences 0302 clinical medicine Lumbar Bone Density Spinal fracture medicine Bone mineral density Bisphosphonate Humans 030212 general & internal medicine Osteoporosis Postmenopausal Bone mineral Alendronate Bone Density Conservation Agents business.industry lcsh:R General Medicine Middle Aged medicine.disease Alkaline Phosphatase medicine.anatomical_structure Hip bone Spinal Fractures Female Bisphosphonate therapy business Peptides Biomarkers Osteoporotic Fractures |
| Zdroj: | Journal of Medical Case Reports Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-4 (2019) |
| ISSN: | 1752-1947 |
| Popis: | Background Osteoporosis is a serious disease that causes bone fragility fractures and increases mortality. Bisphosphonates are the first-line drugs for osteoporosis. However, the gains in bone mineral density by use of bisphosphonates alone are limited. Case presentation We describe the clinical outcome of a Japanese woman with osteoporosis treated with bisphosphonates after multiple spinal fractures. After 3 years of treatment with the bisphosphonate alendronate, her lumbar bone mineral density and bilateral hip bone mineral density markedly increased by 61.9% and 32.5%, respectively. Conclusion We considered that our patient’s multiple fractures had caused a decrease in bone mineral density, which naturally improved with fracture healing to enhance the increase in bone mineral density with bisphosphonate treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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