Effect of Testosterone Level on Mortality in Patients With Left Ventricular Assist Device
| Autor: | Mustafa Özbaran, Sanem Nalbantgil, Evrim Şimşek, Pelin Öztürk, Salih Kilic, Ilgin Yildirim, Hatice Kemal, Tahir Yagdi, Çağatay Engin |
|---|---|
| Přispěvatelé: | Ege Üniversitesi |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Cumulative survival Risk Factors Internal medicine medicine Humans In patient Testosterone Retrospective Studies Heart Failure Transplantation business.industry Testosterone (patch) Middle Aged medicine.disease Survival Rate Testosterone level Mortality data Ventricular assist device Heart failure Multivariate Analysis Cardiology Plasma testosterone measurement Surgery Heart-Assist Devices business |
| Zdroj: | Transplantation proceedings. 51(10) |
| ISSN: | 1873-2623 |
| Popis: | WOS: 000504951000038 PubMed: 31733796 Background and objectives. Testosterone deficiency is associated with mortality in patients with heart failure; however, its effects on patients undergoing Left Ventricular Assist Device (LVAD) implantation are unclear. We investigated the role of total testosterone (TT) and free testosterone (FT) levels on mortality undergoing LVAD implantation. Methods. Between December 2010 and December 2014, 101 consecutive male patients who underwent LVAD implantation and had plasma testosterone measurement (TT and FT) in the last month before operation were included in the study. Demographics, follow-up, and mortality data were analyzed retrospectively. Results. the mean age of the patients was 51.7 +/- 11 years. TT and FT levels were in the below normal range of 31.6% (n = 32) and 65.3% (n = 66) of the patients, respectively. the mean follow-up time was 355 +/- 268 days, and 32 (31%) patients died during follow-up. Cumulative survival rates were significantly worse in patients with low TT and FT than patients in the normal range (P |
| Databáze: | OpenAIRE |
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