Increased diffusion and decreased perfusion in epiphyses of femoral heads detected via intravoxel incoherent motion after closed reduction in children with developmental dysplasia of the hip
| Autor: | Zhi Wang, Shuang Xia, Xue Ning Zhang, Zhong Li Zhang, Jian Ping Yang, Xiang Hong Meng |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_treatment 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Image Processing Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging In patient Diffusion (business) Hip Dislocation Congenital Intravoxel incoherent motion Reduction (orthopedic surgery) 030222 orthopedics Radiological and Ultrasound Technology Developmental dysplasia business.industry Infant Femur Head General Medicine Magnetic Resonance Imaging Female Blood supply business Nuclear medicine Epiphyses Perfusion |
| Zdroj: | Acta Radiologica. 59:1130-1138 |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1177/0284185117748489 |
| Popis: | Background Patients with developmental dysplasia of the hip (DDH) may have decreased blood supply to the femoral heads. Finding a non-invasive method to evaluate whether the femoral heads in patients with DDH are ischemic is paramount for orthopedic surgeons. Purpose To identify whether parameters reflecting perfusion and diffusion in intravoxel incoherent motion (IVIM) sequences can be used to assess ischemia in femoral heads in patients with DDH after closed reduction. Material and Methods Twenty-eight patients with DDH who had undergone closed reduction were enrolled. IVIM data were acquired using a 3-T magnetic resonance scanner, regions of interest were placed on the epiphyses; ADCslow, ADCfast, f, and ADCfast×f were measured. A Mann–Whitney U test was performed to compare ADCslow, ADCfast, f, and ADCfast×f between the lesion and control sides. Receiver operating characteristic curves were generated with respective cut-off values. The lesion sides were classified based on the International Hip Dysplasia Institute (IHDI) classification. ADCslow, ADCfast, f, and ADCfast×f were compared among the groups. Results ADCslow was higher and ADCfast, f, and ADCfast×f were lower on the lesion sides ( P = 0.000–0.002). The optimal cut-off value for ADCfast×f, ADCfast, ADCslow, and f were 0.030, 0.626, 0.000251, and 0.636, respectively. Higher IHDI classification scores on the lesion side were associated with lower ADCfast, f, and ADCfast×f, and higher ADCslow values. Conclusion IVIM is a promising method to investigate the perfusion and diffusion of epiphyses of femoral heads. |
| Databáze: | OpenAIRE |
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