The domino chemistry approach to molecular complexity: high-yielding bis-hetero intramolecular Diels–Alder reactions with ketone components
| Autor: | Angeline Chanu, Siméon Arseniyadis, Aurelien Commeureuc, Isabel Castellote, Imad Safir |
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| Přispěvatelé: | Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC) |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
chemistry.chemical_classification
Molecular complexity Ketone Bicyclic molecule 010405 organic chemistry Stereochemistry [CHIM.ORGA]Chemical Sciences/Organic chemistry Organic Chemistry Iodobenzene Sequence (biology) General Medicine 010402 general chemistry High yielding Combinatorial chemistry 01 natural sciences Catalysis Domino 0104 chemical sciences Inorganic Chemistry chemistry.chemical_compound Template chemistry Intramolecular force Physical and Theoretical Chemistry ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Tetrahedron: Asymmetry Tetrahedron: Asymmetry, Elsevier, 2006, 17(17), pp.2565-2591. ⟨10.1016/j.tetasy.2006.09.003⟩ |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/j.tetasy.2006.09.003⟩ |
| Popis: | The bis-keto-hetero-IMDA option, with two ketone components (both the heterodiene and heterodienophile moieties) has been examined in several representative domino templates with the aim of ultimately developing efficient methods for the synthesis of structurally complex natural products. The domino sequence could also be activated efficiently by utilizing the less toxic iodobenzene diacetate as the oxidative cleavage/[4+2] promoter while it is unbiased to the nature of substitution around the bicyclic framework. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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