Placental abruption and perinatal death
Autor: | Nina B. Kyrklund-Blomberg, Sven Cnattingius, Gerhard Gennser |
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Rok vydání: | 2001 |
Předmět: |
Adult
Infertility medicine.medical_specialty Epidemiology Population Logistic regression Essential hypertension Pregnancy Risk Factors Placenta Infant Mortality Odds Ratio medicine Humans education Abruptio Placentae Sweden Gynecology education.field_of_study Placental abruption Obstetrics business.industry Data Collection Smoking Infant Newborn Odds ratio medicine.disease Pregnancy Complications Logistic Models medicine.anatomical_structure Socioeconomic Factors Data Interpretation Statistical Pediatrics Perinatology and Child Health Female business Premature rupture of membranes |
Zdroj: | Paediatric and Perinatal Epidemiology. 15:290-297 |
ISSN: | 1365-3016 0269-5022 |
DOI: | 10.1046/j.1365-3016.2001.00352.x |
Popis: | Studies of risk factors for abruptio placentae (AP) are partly conflicting and studies of risk factors for perinatal death in these pregnancies are scarce. Using the population-based Swedish Birth Registry from 1987 to 1993, we were able to study these risks in 795,459 singleton pregnancies. Logistic regression analysis was used to estimate odds ratios (OR) for risk of AP and risk of perinatal death in pregnancies with and without AP. Risk factors for AP were: age, primiparity, high parity, not cohabiting with infant's father, low education, smoking, infertility, pregestational diabetes, essential hypertension, pregnancy-induced hypertensive diseases, preterm premature rupture of membranes, preterm birth and small-for-gestational-age (SGA) births. Risk factors for perinatal death in pregnancies with placental abruption were smoking (1--9 and > or =10 cigarettes/day; OR 1.4 and 1.7 respectively), severe pre-eclampsia (OR 2.0) and SGA (OR 1.9), whereas in pregnancies without abruption, risks were also increased in maternal age > or =35 years, primiparity, infertility, essential hypertension and pregestational diabetes. These findings support the theory that, in cases of AP, a general impairment of the placenta and/or a defect placentation may be fatal. |
Databáze: | OpenAIRE |
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