Assessing mobility and balance in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay population: Validity and reliability of four outcome measures

Autor: Cynthia Gagnon, Jean Mathieu, Bernard Brais, Caroline Lavoie, Isabelle Côté, Matthis Synofzik, Isabelle Lessard
Rok vydání: 2017
Předmět:
Male
030506 rehabilitation
Intraclass correlation
physiopathology [Spinocerebellar Ataxias]
Validity
diagnosis [Muscle Spasticity]
Severity of Illness Index
0302 clinical medicine
congenital [Spinocerebellar Ataxias]
Medicine
diagnosis [Spinocerebellar Ataxias]
Postural Balance
Reliability (statistics)
education.field_of_study
Sex Characteristics
Middle Aged
Biomechanical Phenomena
Neurology
Muscle Spasticity
Spinocerebellar ataxia
Disease Progression
Female
0305 other medical science
Adult
medicine.medical_specialty
Adolescent
Movement
Population
Walk Test
03 medical and health sciences
Young Adult
Physical medicine and rehabilitation
Humans
Spinocerebellar Ataxias
ddc:610
education
physiopathology [Muscle Spasticity]
business.industry
methods [Walk Test]
Construct validity
Reproducibility of Results
rehabilitation [Spinocerebellar Ataxias]
medicine.disease
Inter-rater reliability
Wheelchairs
Berg Balance Scale
rehabilitation [Muscle Spasticity]
Neurology (clinical)
business
human activities
030217 neurology & neurosurgery
Zdroj: Journal of the neurological sciences 390, 4-9 (2018). doi:10.1016/j.jns.2018.03.033
ISSN: 1878-5883
DOI: 10.1016/j.jns.2018.03.033
Popis: Objective To assess the construct validity of the 10-Meter Walk Test (10mWT), Six-Minute Walk Test (6MWT), Berg Balance Scale (BERG), and Timed Up and Go (TUG) in adults with Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS), in addition to the interrater reliability of the 10mWT and 6MWT. Methods Reliability was determined using the intraclass correlation coefficient (ICC). Validity was determined first by correlating the 10mWT, 6MWT, BERG, and TUG with participant's age, lower limb coordination, and disease severity, and then by assessing their capacity to distinguish between participants based on sex and disease stages. Results Interrater reliability of the 10mWT at both comfortable and maximum speed as well as the 6MWT is excellent (ICC = 0.97–0.99). Construct validity of the four tests was confirmed, as showed by the high correlations with age, lower limb coordination, and overall disease severity (ρ = 0.64–0.97). Conclusions The four tests assessed for their metrological properties in this study showed to be valid instruments to use in the ARSACS population. The 10mWT and 6MWT are also highly reliable. BERG and TUG reliability will need to be assess in a future study.
Databáze: OpenAIRE