Analysing ventricular fibrillation ECG-signals and predicting defibrillation success during cardiopulmonary resuscitation employing N(α)-histograms
| Autor: | Volker Wenzel, Anton Amann, Hans-Ulrich Strohmenger, Karl H. Lindner, Johannes Bonatti, Herwig Antretter, Ulrich Achleitner, Josef Rieder, Anette C. Krismer, Wolfgang G. Voelckel |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Vasopressin Epinephrine Swine Vasopressins Defibrillation medicine.medical_treatment Electric Countershock Emergency Nursing Sensitivity and Specificity Electrocardiography Predictive Value of Tests Outcome Assessment Health Care medicine Animals Vasoconstrictor Agents Cardiopulmonary resuscitation Fibrillation Analysis of Variance Fourier Analysis medicine.diagnostic_test business.industry Spectrum Analysis medicine.disease Cardiopulmonary Resuscitation Disease Models Animal Predictive value of tests Anesthesia Ventricular Fibrillation Ventricular fibrillation Emergency Medicine Female medicine.symptom Cardiology and Cardiovascular Medicine business Algorithms medicine.drug |
| Zdroj: | Resuscitation. 50:77-85 |
| ISSN: | 0300-9572 |
| DOI: | 10.1016/s0300-9572(01)00322-7 |
| Popis: | Mean fibrillation frequency may predict defibrillation success during cardiopulmonary resuscitation (CPR). N(alpha)-histogram analysis should be investigated as an alternative. After 4 min of cardiac arrest, and 3 versus 8 min of CPR, 25 pigs received either vasopressin or epinephrine (0.4, 0.4, and 0.8 U/kg vasopressin versus 45, 45, and 200 microg/kg epinephrine) every 5 min with defibrillation at 22 min. Before defibrillation, the N(alpha)-parameter histogramstart/histogramwidth and the mean fibrillation frequency in resuscitated versus non-resuscitated pigs were 2.9+/-0.4 versus 1.7+/-0.5 (P=0.0000005); and 9.5+/-1.7 versus 6.9+/-0.7 (P=0.0003). During the last minute prior to defibrillation, histogramstart/histogramwidth of > or =2.3 versus mean fibrillation frequency > or =8 Hz predicted successful defibrillation with subsequent return of a spontaneous circulation for more than 60 min with sensitivity, specificity, positive predictive value and negative predictive value of 94 versus 82%, 96 versus 89%, 98 versus 93% and 90 versus 74%, respectively. We conclude, that N(alpha)-analysis was superior to mean fibrillation frequency analysis during CPR in predicting defibrillation success, and distinction between vasopressin versus epinephrine effects. |
| Databáze: | OpenAIRE |
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