Dominant behaviours in the expression of human carbonic anhydrase hCA I activity
| Autor: | Muhammet Tanc, Jean-Yves Winum, Claudiu T. Supuran, M. Yahia M. Abdelrahim, Mihail Barboiu |
|---|---|
| Přispěvatelé: | Institut Européen des membranes (IEM), Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM), Laboratorio di Chimica Bioinorganica (LCBI), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI) |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Carbonic Anhydrase I
genetic structures Catalysis Structure-Activity Relationship Carbonic anhydrase mental disorders Materials Chemistry Humans [CHIM]Chemical Sciences cardiovascular diseases Carbonic Anhydrase Inhibitors ComputingMilieux_MISCELLANEOUS biology Molecular Structure Chemistry Metals and Alloys nutritional and metabolic diseases General Chemistry 3. Good health Surfaces Coatings and Films Electronic Optical and Magnetic Materials Enzyme Activation Biochemistry Ceramics and Composites biology.protein sense organs |
| Zdroj: | Chemical Communications Chemical Communications, Royal Society of Chemistry, 2014, 50 (59), pp.8043-8046. ⟨10.1039/c4cc03289f⟩ |
| ISSN: | 1359-7345 1364-548X |
| Popis: | Here we describe the screening via Dynamic Deconvolution of DCLs of inhibitors (CAIs) and activators (CAAs) of hCA I. The inhibitory effects dominate over the activating ones, while the CAAs may be identified in the absence of CAIs. |
| Databáze: | OpenAIRE |
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