Chlorine disinfection increases both intracellular and extracellular antibiotic resistance genes in a full-scale wastewater treatment plant
| Autor: | Min Jin, Jun-Wen Li, Dong Yang, Hong-mei Qu, Shan-Shan Liu, Zhiqiang Shen, Ai-ming Hou, Jianhua Guo, Zhigang Qiu, Hui Hu, Weili Liu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Environmental Engineering
Halogenation Tetracycline 0211 other engineering and technologies chemistry.chemical_element 02 engineering and technology Wastewater 010501 environmental sciences 01 natural sciences Water Purification Microbiology chemistry.chemical_compound Antibiotic resistance Drug Resistance Bacterial Escherichia coli polycyclic compounds medicine Chlorine Waste Management and Disposal Effluent 0105 earth and related environmental sciences Water Science and Technology Civil and Structural Engineering 021110 strategic defence & security studies Chlorine dioxide Chemistry Escherichia coli Proteins Ecological Modeling Drug Resistance Microbial Pollution 6. Clean water Anti-Bacterial Agents Disinfection Vancomycin Sewage treatment Rifampicin Disinfectants medicine.drug |
| Zdroj: | Water Research. 136:131-136 |
| ISSN: | 0043-1354 |
| DOI: | 10.1016/j.watres.2018.02.036 |
| Popis: | The emergence and spread of antibiotic resistance has posed a major threat to both human health and environmental ecosystem. Although the disinfection has been proved to be efficient to control the occurrence of pathogens, little effort is dedicated to revealing potential impacts of disinfection on transmission of antibiotic resistance genes (ARGs), particularly for free-living ARGs in final disinfected effluent of urban wastewater treatment plants (UWWTP). Here, we investigated the effects of chlorine disinfection on the occurrence and concentration of both extracellular ARGs (eARGs) and intracellular ARGs (iARGs) in a full-scale UWWTP over a year. We reported that the concentrations of both eARGs and iARGs would be increased by the disinfection with chlorine dioxide (ClO2). Specifically, chlorination preferentially increased the abundances of eARGs against macrolide (ermB), tetracycline (tetA, tetB and tetC), sulfonamide (sul1, sul2 and sul3), β-lactam (ampC), aminoglycosides (aph(2')-Id), rifampicin (katG) and vancomycin (vanA) up to 3.8 folds. Similarly, the abundances of iARGs were also increased up to 7.8 folds after chlorination. In terms of correlation analyses, the abundance of Escherichia coli before chlorination showed a strong positive correlation with the total eARG concentration, while lower temperature and higher ammonium concentration were assumed to be associated with the concentration of iARGs. This study suggests the chlorine disinfection could increase the abundances of both iARGs and eARGs, thereby posing risk of the dissemination of antibiotic resistance in environments. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect