Effect of Vaccination on Transmission of HPAI H5N1: The Effect of a Single Vaccination Dose on Transmission of Highly Pathogenic Avian Influanza H5N1 in Peking Ducks
| Autor: | J.A. van der Goot, M.C.M. de Jong, R.M. van Boven, Guus Koch |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Veterinary medicine
animal structures animal diseases Kwantitatieve Veterinaire Epidemiologie Biology medicine.disease_cause Virus Serology Herd immunity Food Animals CIDC - Division Virology evolution medicine Animals viruses hong-kong Influenza A Virus H5N1 Subtype General Immunology and Microbiology business.industry Transmission (medicine) CIDC - Divisie Virologie Vaccination Outbreak virus diseases Quantitative Veterinary Epidemiology Building and Construction Poultry farming asia Virology Influenza A virus subtype H5N1 Ducks Influenza Vaccines ASG Infectieziekten Influenza in Birds outbreaks WIAS chickens Animal Science and Zoology geese business |
| Zdroj: | Avian Diseases 51 (2007) Avian Diseases, 51, 323-324 |
| ISSN: | 0005-2086 |
| Popis: | The highly pathogenic H5N1 avian influenza virus is widespread among domestic ducks throughout Southeast Asia. Many aspects of the poultry industry and social habits hinder the containment and eradication of AI. Vaccination is often put forward as a tool for the control of AI. However, vaccination will only lead to eradication when it reduces the virus spread to such an extent that herd immunity is obtained. To study the effect of a single vaccination dose on the transmission of H5N1 in domestic ducks we performed experiments in which infected and uninfected ducks were housed together and the infection chain was monitored by means of virus isolation and serology. Specifically, Peking ducks were vaccinated with A/Chicken/Mexico/232/94/ CPA H5N2 and challenged with A/Chicken/GxLA/1204/04 H5N1 one week after vaccination. In both the control and vaccinated groups all inoculated and contact animals were quickly infected. However, the disease signs and mortality differed between the control and treatment groups. This finding may have important implications for the control of H5N1 by means of vaccination. |
| Databáze: | OpenAIRE |
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