Anncaliia algerae Microsporidial Myositis

Autor: Kate Clezy, Alexander C. Outhred, Stephen W. Reddel, Vivienne Tobias, Andrew S. Field, Damien Stark, Elaine Y.L. Cheong, Susan Brammah, James V. Bertouch, Matthew R Watts, Michael V. Prowse, Bobby Chacko, Deborah Marriott, Cameron E. Webb, Chiwai Tong, Renee C.F. Chan
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 20, Iss 2, Pp 185-191 (2014)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
Popis: Immunosuppression is a risk factor for serious infection in humans.
The insect microsporidian Anncaliia algerae was first described in 2004 as a cause of fatal myositis in an immunosuppressed person from Pennsylvania, USA. Two cases were subsequently reported, and we detail 2 additional cases, including the only nonfatal case. We reviewed all 5 case histories with respect to clinical characteristics, diagnosis, and management and summarized organism life cycle and epidemiology. Before infection, all case-patients were using immunosuppressive medications for rheumatoid arthritis or solid-organ transplantation. Four of the 5 case-patients were from Australia. All diagnoses were confirmed by skeletal muscle biopsy; however, peripheral nerves and other tissues may be infected. The surviving patient received albendazole and had a reduction of immunosuppressive medications and measures to prevent complications. Although insects are the natural hosts for A. algerae, human contact with water contaminated by spores may be a mode of transmission. A. algerae has emerged as a cause of myositis, particularly in coastal Australia.
Databáze: OpenAIRE
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