Evaluation of New Cage Lid with Partitioning Barrier Based on Transmission of CAR Bacillus in Mice
Autor: | Satoru Matsushita, Toshiaki Kokubo |
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Rok vydání: | 2009 |
Předmět: |
medicine.medical_specialty
CAR bacillus Biology General Biochemistry Genetics and Molecular Biology Microbiology Rodent Diseases Mice Stainless steel wire RNA Ribosomal 16S Gram-Negative Bacteria medicine Animals Cilia Animal Husbandry Lung Respiratory Tract Infections General Veterinary Transmission (medicine) Animal cage General Medicine Housing Animal Specific Pathogen-Free Organisms Surgery Quarantine Female Animal Science and Zoology Gram-Negative Bacterial Infections Cage Sentinel Surveillance |
Zdroj: | Experimental Animals. 58:189-192 |
ISSN: | 1881-7122 1341-1357 |
Popis: | We developed a new cage lid made of stainless steel wire mesh and having a screen barrier for partitioning a small laboratory animal cage into compartments. To evaluate the effectiveness of the lid, we tested the transmissibility of Cilia-Associated Respiratory (CAR) bacillus from infected mice to uninfected sentinel mice, which were kept in separate compartments using this lid. Infection from the infected mice to the uninfected mice was confirmed by microbiological, serological, pathological, and molecular diagnostic examinations, as previously observed in an intra-cage contact route. The cage lid that we developed is very useful when uninfected mice are used in quarantine and contagion experiments to prevent fighting among the mice. |
Databáze: | OpenAIRE |
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