Supplementary Figure 1 from CD44 and OTP Are Strong Prognostic Markers for Pulmonary Carcinoids

Autor: Ernst-Jan M. Speel, Frans C.S. Ramaekers, Manon van Engeland, Wim Van Criekinge, Marco Volante, Erik Thunnissen, Martina Rudelius, Annick Haesevoets, Winand N.M. Dinjens, Anne-Marie C. Dingemans, Robert-Jan van Suylen, Leander Van Neste, Mieke E.R. Henfling, Dorian R.A. Swarts
Rok vydání: 2023
Popis: Representative immunohistochemical staining patterns for CD44 (A), OTP (B) and RET (C). (A) Normal lung tissue adjacent to a carcinoid tumor showing CD44 staining of the bronchial epithelium BE and seromucous glands G (original magnification 100x). The insets show higher magnifications of a seromucous gland and the bronchial epithelium (original magnification 200x). (B) Normal tissue adjacent to carcinoid tumor tissue with cytoplasmic OTP reactivity of the bronchial epithelium and seromucous glands (original magnification 200x), in agreement with the Human Protein Atlas (http://www.proteinatlas.org/ENSG00000171540). The inset shows cytoplasmic reactivity in macrophages (original magnification 400x). (C) Normal tissue adjacent to a carcinoid tumor showing cytoplasmic RET positivity of the bronchial epithelium and seromucous glands (original magnification 200x), in agreement with the Human Protein Atlas (http://www.proteinatlas.org/ENSG00000165731). The inset shows strong membranous RET staining in normal colon (original magnification 200x).
Databáze: OpenAIRE