Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices

Autor: David Filgueiras-Rama, Nicasio Pérez-Castellano, Xavier Viñolas, Juan José González-Ferrer, Aníbal Rodríguez, Ignasi Anguera, José Martínez-Ferrer, Javier Jiménez-Díaz, Javier Alzueta, José María Lillo-Castellano, José Manuel Alfonso-Almazán, Luis Borrego, Javier Cremades García, Arcadio García-Alberola, Julián Pérez-Villacastín, Jorge G. Quintanilla, Victoria Cañadas-Godoy, Juan Carlos Rodríguez-Pérez, José Jalife, Juan Gabriel Martinez, Manuel Marina-Breysse, Luisa Pérez-Álvarez
Přispěvatelé: Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades (España), Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Sociedad Española de Cardiología, NIH - National Heart, Lung, and Blood Institute (NHLBI) (Estados Unidos), National Institutes of Health (Estados Unidos)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
medicine.medical_specialty
Pacemaker
Artificial
animal structures
Atrial fibrillation
Atrial fibrillation progression
Electrical remodeling
Implantable cardioverter-defibrillator
Mobile health
Telemedicine
eHealth
Fibril·lació atrial
endocrine system diseases
medicine.medical_treatment
urologic and male genital diseases
Implantable cardioverter-defibrillator
law.invention
Atrial fibrillation progression
law
Clinical Research
Physiology (medical)
Internal medicine
Atrial Fibrillation
medicine
Humans
In patient
Mobile health
Telecommunication in medicine
Paroxysmal AF
Atrium (architecture)
business.industry
Atrial fibrillation
Atrial Remodeling
Atrial activation
medicine.disease
Electrical remodeling
female genital diseases and pregnancy complications
Frequency spectrum
Telemedicine
Defibrillators
Implantable
Child
Preschool
Cardiology
Artificial cardiac pacemaker
eHealth
Cardiology and Cardiovascular Medicine
business
human activities
Telecomunicació en medicina
Zdroj: Europace
Repisalud
Instituto de Salud Carlos III (ISCIII)
EUROPACE
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname
Dipòsit Digital de la UB
Universidad de Barcelona
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
r-FISABIO. Repositorio Institucional de Producción Científica
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
ISSN: 1532-2092
1099-5129
Popis: Atrial electrical remodelling (AER) is a transitional period associated with the progression and long-term maintenance of atrial fibrillation (AF). We aimed to study the progression of AER in individual patients with implantable devices and AF episodes. Observational multicentre study (51 centres) including 4618 patients with implantable cardioverter-defibrillator +/-resynchronization therapy (ICD/CRT-D) and 352 patients (2 centres) with pacemakers (median follow-up: 3.4 years). Atrial activation rate (AAR) was quantified as the frequency of the dominant peak in the signal spectrum of AF episodes with atrial bipolar electrograms. Patients with complete progression of AER, from paroxysmal AF episodes to electrically remodelled persistent AF, were used to depict patient-specific AER slopes. A total of 34 712 AF tracings from 830 patients (87 with pacemakers) were suitable for the study. Complete progression of AER was documented in 216 patients (16 with pacemakers). Patients with persistent AF after completion of AER showed ∼30% faster AAR than patients with paroxysmal AF. The slope of AAR changes during AF progression revealed patient-specific patterns that correlated with the time-to-completion of AER (R2 = 0.85). Pacemaker patients were older than patients with ICD/CRT-Ds (78.3 vs. 67.2 year olds, respectively, P
Databáze: OpenAIRE
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