Short-Term Outcomes of Laparoscopic Proximal Gastrectomy With Double-Tract Reconstruction Versus Laparoscopic Total Gastrectomy for Upper Early Gastric Cancer: A KLASS 05 Randomized Clinical Trial

Autor: Sun-Hwi Hwang, Do Joong Park, Hyung-Ho Kim, Woo Jin Hyung, Hoon Hur, Han-Kwang Yang, Hyuk-Joon Lee, Hyoung-Il Kim, Seong-Ho Kong, Young Woo Kim, Han Hong Lee, Beom Su Kim, Young-Kyu Park, Young-Joon Lee, Sang-Hoon Ahn, In-Seob Lee, Yun-Suhk Suh, Ji-Ho Park, Soyeon Ahn, Sang-Uk Han
Rok vydání: 2022
Předmět:
Zdroj: Journal of gastric cancer. 22(2)
ISSN: 2093-582X
Popis: Laparoscopic proximal gastrectomy with double-tract reconstruction (LPG-DTR) is a function-preserving procedure performed for treating upper early gastric cancer (EGC). However, few studies have compared the outcomes of LPG-DTR with those of laparoscopic total gastrectomy (LTG). This study aimed at comparing the short-term outcomes of LPG-DTR between LTG and upper EGC.For upper-third EGC, a multicenter, prospective, randomized trial was performed to compare those who underwent LPG-DTR with those who underwent LTG. Short-term outcomes, including clinicopathologic results, morbidity, mortality, and postoperative courses, were evaluated using a full analysis set based on the intention-to-treat principle and the per-protocol set.Of the patients, 138 who fulfilled the criteria were randomized to each group. One patient in the LPG-DTR group withdrew consent. Sixty-eight patients underwent LPG-DTR and 69 underwent LTG. The operative time (LPG-DTR=219.4 minutes; LTG=201.8 minutes; PThe short-term outcomes of LPG-DTR for upper EGC were comparable to those of LTG.ClinicalTrials.gov Identifier: NCT02892643.
Databáze: OpenAIRE