Role of relaxin in maternal systemic and renal vascular adaptations during gestation

Autor:	Julianna E. Debrah, Dan O. Debrah, Kirk P. Conrad, Sanjeev G. Shroff, J. Peter Rubin, Jonathan T. McGuane, Mark S. Segal
Rok vydání:	2009
Předmět:	medicine.medical_specialty Hemodynamics Renal function Physiology Vasodilation Kidney General Biochemistry Genetics and Molecular Biology History and Philosophy of Science Pregnancy Internal medicine medicine Animals Humans Relaxin business.industry General Neuroscience Matrix Metalloproteinases Endocrinology medicine.anatomical_structure Vascular resistance Gestation Female Vascular Resistance sense organs business Endothelin receptor Hormone
Zdroj:	Annals of the New York Academy of Sciences. 1160
ISSN:	1749-6632
Popis:	In this paper, the hemodynamic changes of normal pregnancy are reviewed and the underlying hormonal and molecular mechanisms are discussed. Among other findings related to these phenomena, our previous work has demonstrated the importance of relaxin in systemic and renal vascular as well as osmoregulatory changes during gestation. These findings are summarized, and new concepts related to the function of relaxin in blood vessels are presented. Finally, work in progress is briefly outlined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323bfe3bf49c239baab336cdf3bee61a https://pubmed.ncbi.nlm.nih.gov/19416209 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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