Molecular epidemiological analysis of Japanese encephalitis virus in China
| Autor: | Jia Ke Zhang, Ichiro Kurane, Xiao Feng Liang, Qing Tang, Zong Yu Hao, Shi Hong Fu, Huan Yu Wang, Guo Dong Liang, Shigeru Tajima, Hai Lin Zhang, Tomohiko Takasaki, Wei Zhong Yang, Xiao-hong Sun, Zhao Xiao Wang, Akira Kotaki |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
China
Genes Viral viruses Molecular Sequence Data Sequence Homology Ceratopogonidae Virus Viral Proteins Flaviviridae Viral Envelope Proteins Virology Genotype medicine Animals Humans Encephalitis Japanese Phylogeny Cerebrospinal Fluid Encephalitis Virus Japanese Molecular Epidemiology Membrane Glycoproteins Phylogenetic tree biology Molecular epidemiology Sequence Analysis DNA Japanese encephalitis medicine.disease biology.organism_classification Flavivirus Blood Culicidae RNA Viral Encephalitis |
| Zdroj: | Journal of General Virology. 88:885-894 |
| ISSN: | 1465-2099 0022-1317 |
| DOI: | 10.1099/vir.0.82185-0 |
| Popis: | Sixty-two new Japanese encephalitis virus (JEV) isolates were obtained from mosquitoes, biting midges, human cerebrospinal fluid and human blood samples in China during 2002–2005. The E and prM genes were sequenced and phylogenetic analyses were performed with 38 JEV other isolates from China and 36 JEV strains from other countries. Phylogenetic trees based on the E and prM gene sequences were similar. The results indicate that: (i) recent JEV isolates from China are divided into two genotypes, genotype 1 and genotype 3; (ii) recent JEV isolates from China are grouped into the same clusters within genotypes 1 and 3; and (iii) genotype 1 JEV strains have been isolated in China since 1979, whilst genotype 3 JEV strains were isolated before the 1970s. The results suggest that genotype 1 JEV was introduced to China around 1979 and that JEV strains belonging to genotypes 1 and 3 circulate in China. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|