Profiling of phytochemical and antioxidant activity of wild mushrooms: Evidence from the in vitro study and phytoconstituent's binding affinity to the human erythrocyte catalase and human glutathione reductase
| Autor: | Mohammad Shahadat Hossain, S. M. Moazzem Hossen, Nazim Uddin Emon, Pracheta Janmeda, Priya Chaudhary, A. T. M. Yusuf |
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| Rok vydání: | 2021 |
| Předmět: |
Antioxidant
biology Chemistry DPPH Nutrition. Foods and food supply In silico medicine.medical_treatment Glutathione reductase catalase mushrooms chemistry.chemical_compound antioxidants Biochemistry Phytochemical Catalase in silico biology.protein medicine In vitro study TX341-641 glutathione reductase Food Science Original Research |
| Zdroj: | Food Science & Nutrition Food Science & Nutrition, Vol 10, Iss 1, Pp 88-102 (2022) |
| ISSN: | 2048-7177 |
| Popis: | This study was undertaken to evaluate the appearance of phytochemicals and antioxidant activity of seven wild mushrooms of the University of Chittagong campus. Phytochemical screening was performed using standard methods, whereas DPPH radical scavenging assay was used to elucidate the antioxidant effect. Besides, in silico studies were implemented using the targets of human erythrocyte catalase 3‐amino‐1,2,4‐triazole, human glutathione reductase, and selected compounds. Again, the absorption, distribution, metabolism, elimination and toxicity (ADME/T) analysis has been determined by using online tools. Both Ganoderma lucidum (Curtis) Karst. and Ganoderma applanatum (Pers.) Pat. showed a significant (p This article aggregates consolidates and validates free radical scavenging activity of seven wild mushrooms along with their phytoconstituent’s binding affinity to the human erythrocyte catalase. |
| Databáze: | OpenAIRE |
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