fimA-folDgenes linkage inSalmonellaidentifies a putative junctional site of chromosomal rearrangement in the enterobacterial genome
| Autor: | Giuseppe Satta, Patrizia Muscas, Alessandra Chiesurin, Gian Maria Rossolini |
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| Rok vydání: | 1994 |
| Předmět: |
Salmonella
Genetic Linkage Molecular Sequence Data Chromosomal rearrangement Biology medicine.disease_cause Microbiology Bacterial Proteins Aminohydrolases Multienzyme Complexes Genetic linkage Sequence Homology Nucleic Acid Gene cluster Genetics medicine Amino Acid Sequence Molecular Biology Gene Conserved Sequence Regulator gene Gene Rearrangement Methylenetetrahydrofolate Dehydrogenase (NADP) Genome Base Sequence Gene rearrangement biochemical phenomena metabolism and nutrition Molecular biology Multigene Family Chromosomal region bacteria Fimbriae Proteins |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1574-6968 0378-1097 |
| DOI: | 10.1111/j.1574-6968.1994.tb06908.x |
| Popis: | Analysis of the Salmonella chromosomal region located upstream of the fimA gene (coding for the major type 1 fimbrial subunit) showed a close linkage of this gene to the folD gene (coding for the enzyme 5,10-methylenetetrahydrofolate dehydrogenase/5, 10-methenyltetrahydrofolate cyclohydrolase), indicating that the fim gene cluster of Salmonella, unlike that of Escherichia coli, has no regulatory genes located upstream of fimA and apparently terminates with this gene. The respective locations of the fim and folD genes in the E. coli and Salmonella genetic maps suggests that the fimA-folD intergenic region of Salmonella encompasses a junctional site of a genetic rearrangement that probably originated from the different chromosomal location of the fim genes in these species. |
| Databáze: | OpenAIRE |
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