The impact of SARS-CoV-2 on the cystic fibrosis foundation therapeutics development network
| Autor: | Amy Hoffman, Christopher H. Goss, Patricia Burks, David P. Nichols, John P. Clancy, George Z. Retsch-Bogart, Jill M. VanDalfsen, K. Pearson, Nicole Mayer-Hamblett, Daniel B. Rosenbluth |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Spirometry Pulmonary and Respiratory Medicine medicine.medical_specialty Biomedical Research Electronic data capture Cystic Fibrosis Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Short Communication Cystic fibrosis Clinical research 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires Pandemic medicine Humans Pediatrics Perinatology and Child Health Intensive care medicine Data collection medicine.diagnostic_test business.industry SARS-CoV-2 COVID-19 medicine.disease Coronavirus 030104 developmental biology 030228 respiratory system Research Design Pediatrics Perinatology and Child Health Severe acute respiratory syndrome coronavirus business Foundations |
| Zdroj: | Journal of Cystic Fibrosis |
| ISSN: | 1873-5010 1569-1993 |
| Popis: | Highlights • The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) global pandemic has significantly impacted CF clinical research. • An electronic survey was sent to Therapeutic Development Network (TDN) sites to monitor the impact. • SARS-CoV-2 had an early impact on participant enrollment, research team stability, and procedures such as spirometry and sputum induction. • Trends steadily improved over the months as research activities began to recover across the TDN. • SARS-CoV-2 highlights new opportunities to expand CF research focusing on data collection outside of research centers and increased access for remote participation. The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) global pandemic significantly impacted CF clinical research within the Cystic Fibrosis Foundation Therapeutics Development Network (CFF TDN). A Research Electronic Data Capture (REDCap) survey was developed and sent to network sites to monitor and understand the impact on research teams, ongoing and anticipated clinical research, and specific clinical and research procedures. Key findings indicated an early impact on participant enrollment, research team stability, and procedures such as spirometry and sputum induction. These trends steadily improved over the months as research activities began to recover across the TDN. While SARS-CoV-2 created a significant challenge it also highlights new opportunities to expand CF research with greater focus on data collection outside of research centers and increased access for remote participation. |
| Databáze: | OpenAIRE |
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