Commensal Fungi in Health and Disease
Autor: | David M. Underhill, Jose J. Limon, Joseph H. Skalski |
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Rok vydání: | 2017 |
Předmět: |
Lung Diseases
0301 basic medicine Host immunity Mycobiota Respiratory System Urogenital System Disease Biology Skin Diseases Microbiology Article 03 medical and health sciences Fungal Microbiota Virology medicine Humans Microbiome DNA Fungal Symbiosis Immunity Mucosal Skin Metabolic Syndrome Genetics Bacteria Microbiota Fungi medicine.disease Gastrointestinal Tract 030104 developmental biology Host-Pathogen Interactions Dysbiosis Microbial Interactions Parasitology Mycobiome |
Zdroj: | Cell Host & Microbe. 22:156-165 |
ISSN: | 1931-3128 |
Popis: | Fungi are increasingly being recognized as common members of the microbiomes found on nearly all mucosal surfaces, and interest is growing in understanding how these organisms may contribute to health and disease. In this review, we investigate recent developments in our understanding of the fungal microbiota or "mycobiota" including challenges faced in characterizing it, where these organisms are found, their diversity, and how they interact with host immunity. Growing evidence indicates that, like the bacterial microbiota, the fungal microbiota is often altered in disease states, and increasingly studies are being designed to probe the functional consequences of such fungal dysbiosis on health and disease. |
Databáze: | OpenAIRE |
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