Inactivation of glutamic-aspartic transaminase by irradiation
| Autor: | A. Fisher, Esmond E. Snell, F. Schlenk |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
chemistry.chemical_classification
biology Pyridoxine General Biochemistry Genetics and Molecular Biology Cofactor Transaminase Radiation Effects chemistry.chemical_compound Enzyme chemistry Glutamic-aspartic transaminase Biochemistry Ultraviolet light biology.protein medicine Irradiation Aspartate Aminotransferases Pyridoxal Transaminases medicine.drug |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 61 |
| ISSN: | 0037-9727 |
| Popis: | SummaryGlutamic-aspartic transaminase is inactivated by sunlight and by ultraviolet light. Destruction of enzymatic activity by these agents parallels the destruction of vitamin B6, a derivative of which is present as the prosthetic group of the enzyme.1234 The irradiated enzyme is not reactivated by addition of pyridoxine, pyridoxal, pyridox-amine or boiled tissue extracts. Irradiation with X-rays leaves the enzyme intact. |
| Databáze: | OpenAIRE |
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