Effects of a Vasopressin Antagonist in Women with Dysmenorrhea
| Autor: | Lil Valentin, Per Melin, Karel Marsal, Anja Broeders, Povilas Sladkevicius, Hans Kindahl |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
medicine.medical_specialty Vasopressin Vasopressins medicine.drug_class Uterus Dinoprost Contractility Uterine Contraction Hormone Antagonists Vasotocin Double-Blind Method Dysmenorrhea Internal medicine medicine.artery medicine Humans Uterine artery Cross-Over Studies business.industry Antagonist Obstetrics and Gynecology Atosiban Endocrinology medicine.anatomical_structure Reproductive Medicine In utero Female business Blood Flow Velocity hormones hormone substitutes and hormone antagonists Vasopressin Antagonists medicine.drug |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000010319 |
| Popis: | We compared menstrual pain, uterine contractility and blood circulation, and plasma concentrations of vasopressin and prostaglandin F2α metabolite in women with versus without primary dysmenorrhea, and determined the effects of a vasopressin antagonist, 1-deamino-2-D-Tyr(OEt)-4-Thr-8-Orn-oxytocin (Atosiban), on these parameters. Our results do not support the contention that vasopressin is involved in the etiology of dysmenorrhea, plasma concentrations of vasopressin being similar in dysmenorrheic women and controls, and the vasopressin antagonist Atosiban having no effect on menstrual pain, intrauterine pressure or uterine artery pulsatility index in dysmenorrheic women. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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