Renal and systemic hemodynamic responses to sustained submaximal exertion in horses
| Autor: | William W. Muir, K. H. McKeever, L. M. Schmall, Catherine W. Kohn, Kenneth W. Hinchcliff |
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| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Cardiac output Physiology Physical Exertion Renal function Hemodynamics Renal Circulation Physiology (medical) Internal medicine Heart rate Animals Medicine Horses Exertion Renal circulation business.industry Carbon Dioxide Hydrogen-Ion Concentration Filtration fraction Oxygen medicine.anatomical_structure Endocrinology Renal blood flow Cardiology Female business |
| Zdroj: | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 258:R1177-R1183 |
| ISSN: | 1522-1490 0363-6119 |
| DOI: | 10.1152/ajpregu.1990.258.5.r1177 |
| Popis: | We investigated the effects of 1 h of sustained submaximal exertion on the renal and systemic hemodynamics of six horses. The horses ran on a treadmill at a speed that produced heart rates of 55-60% of each horse's maximum heart rate. Exertion produced heart rates of 121 +/- 6.6 and 126 +/- 6.1 (SE) beats/min after 15 and 60 min, respectively. Cardiac output increased significantly (P less than 0.05) from 70.1 +/- 3.1 to 246.2 +/- 4.7 ml.min-1.kg body wt-1 after 15 min of exertion and thereafter did not change. There was no significant change from rest in p-aminohippuric acid and creatinine clearances, filtration fraction, or renal blood flow during exertion. Plasma total solid concentration and hematocrit increased by 3.8 and 8.6%, respectively, between 20 and 60 min of exertion. Pulmonary artery temperature increased significantly from 37.6 degrees C at rest to 38.6 degrees C at 60 min of exertion. This study demonstrates the ability of the horse to maintain renal hemodynamics similar to resting values and systemic hemodynamics at steady-state values despite hemoconcentration and increased body temperature during sustained submaximal exertion. |
| Databáze: | OpenAIRE |
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