Hyperbaric Oxygen Therapy for Reconstructive Urology Wounds: A Case Series

Autor: Oley, Mendy Hatibie, Oley, Maximillian Christian, Iskandar, Ari Astram Adhiatma, Toreh, Christof, Tulong, Marcella Tirsa, Faruk, Muhammad
Rok vydání: 2021
Předmět:
Zdroj: Research and Reports in Urology
ISSN: 2253-2447
DOI: 10.2147/rru.s331161
Popis: Mendy Hatibie Oley,1– 3 Maximillian Christian Oley,3– 5 Ari Astram Adhiatma Iskandar,6,7 Christof Toreh,6,7 Marcella Tirsa Tulong,3 Muhammad Faruk8 1Plastic Reconstructive and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia; 2Plastic Reconstructive and Aesthetic Surgery Division, Department of Surgery, R. D. Kandou Hospital, Manado, Indonesia; 3Hyperbaric Centre Siloam Hospital, Manado, Indonesia; 4Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia; 5Division of Neurosurgery, Department of Surgery, R. D. Kandou Hospital, Manado, Indonesia; 6Division of Urology, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia; 7Division of Urology, Department of Surgery, R. D. Kandou Hospital, Manado, Indonesia; 8Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, IndonesiaCorrespondence: Mendy Hatibie OleyPlastic Reconstructive and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Jalan Raya Tanawangko No. 56, Malalayang Satu Barat, Malalayang, Manado, North Sulawesi, 95162, IndonesiaFax +62 431-863786Email mendy.hatibie@unsrat.ac.idIntroduction: Hyperbaric oxygen therapy (HBOT) has been applied to urological wound healing because it reduces inflammation, facilitates angiogenesis through endothelial proliferation, stimulates fibroblast, lymphocyte, and macrophage activity, and exerts bactericidal effects. Thus, we present a case series of reconstructive urology wounds treated adjunctively with HBOT.Case Report: Here, we present the cases of eight patients with urology wounds who underwent different forms of surgical reconstruction. Three patients received penile shaft silicone fluid injection with repeated infection, successful excision of a siliconoma mass, and defect closure with a full-thickness skin graft. One patient had hypospadias and multiple post-closure fistulae. Two patients had bilateral keystone flaps (post total penectomy, orchidectomy, perineotomy, and penile tumors) closed with a split-thickness skin graft (STSG). Two patients had Fournier’s gangrene in their genital area, for which the wound was debrided and then closed with a STSG. All patients received HBOT after surgery with satisfying results.Conclusion: HBOT promotes wound healing and improves graft integration in patients undergoing urological reconstructive surgery.Keywords: hyperbaric oxygen therapy, tissue reconstruction, would healing, adjunctive treatment, urology
Databáze: OpenAIRE