A comparative study on the efficacy of treatment with 585 nm pulsed dye laser and ultraviolet B-TL01 in plaque type psoriasis
| Autor: | Bhupendra Tank, H. A. Martino Neumann, Jaap de Leeuw, Hilde Both, Tamar Nijsten, Rosanne G. Van Lingen |
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| Přispěvatelé: | Dermatology |
| Rok vydání: | 2008 |
| Předmět: |
Light therapy
Adult Male medicine.medical_specialty medicine.medical_treatment Lasers Dye Dermatology Auto-immunity transplantation and immunotherapy [N4i 4] law.invention stomatognathic system Randomized controlled trial law Psoriasis medicine Humans In patient Prospective Studies Low-Level Light Therapy Prospective cohort study Dye laser business.industry Ultraviolet b General Medicine Plaque type psoriasis Middle Aged medicine.disease Surgery Female Ultraviolet Therapy business |
| Zdroj: | Dermatologic Surgery, 35(1), 80-91. Lippincott Williams & Wilkins Dermatologic Surgery, 35, 1, pp. 80-91 Dermatologic Surgery, 35, 80-91 |
| ISSN: | 1524-4725 1076-0512 |
| Popis: | Contains fulltext : 81574.pdf (Publisher’s version ) (Closed access) BACKGROUND: Narrow-band ultraviolet-B and pulsed dye laser (PDL) affect psoriasis but via different pathways. OBJECTIVE: To compare the results of PDL with ultraviolet-B light therapy (UVB) and to look for synergism of both therapies in patients with plaque type psoriasis. METHODS: In each eligible individual, four similar target plaques were selected, and halves of these plaques were treated using PDL, UVB, or a combination of PDL and UVB or were not treated. Results were recorded single-blind using the Physician's Global Assessment score at study enrolment and Week 13. Nonparametric, paired statistical tests were used to test for differences within and between therapies.The results were also analyzed after dichotomization of the changes in the Physician's Global Assessment score into responsive and nonresponsive to treatment. RESULTS: A significant improvement of the psoriasis lesions was noted at Week 13 (P |
| Databáze: | OpenAIRE |
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