Plasma Glutamate Dehydrogenase: Clinical Application in Patients With Alcoholic Liver Disease
Autor: | Charles S. Lieber, Theresa M. Worner |
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Rok vydání: | 1980 |
Předmět: |
Male
medicine.medical_specialty Alcoholic liver disease Pathology Time Factors medicine.medical_treatment Medicine (miscellaneous) Toxicology Gastroenterology chemistry.chemical_compound Glutamate Dehydrogenase Internal medicine medicine Humans In patient Liver Diseases Alcoholic Normal range Ethanol medicine.diagnostic_test business.industry Glutamate dehydrogenase Alcohol detoxification medicine.disease Enzymes Psychiatry and Mental health Liver chemistry Liver biopsy Time course Female business |
Zdroj: | Alcoholism: Clinical and Experimental Research. 4:431-434 |
ISSN: | 0145-6008 |
DOI: | 10.1111/j.1530-0277.1980.tb04845.x |
Popis: | The time course of plasma glutamate dehydrogenase (GDH) elevation was studied in 42 male alcoholics admitted for alcohol detoxification or for the treatment of medical complications of alcoholism and in 2 volunteers consuming 2 g/kg/day of ethanol under metabolic ward conditions. GDH values were usually highest during or immediately after cessation of drinking; thereafter, they fell rapidly toward the normal range. Early GDH values correlated well with liver histology in 37 patients who subsequently underwent diagnostic liver biopsy. |
Databáze: | OpenAIRE |
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