Plasma Glutamate Dehydrogenase: Clinical Application in Patients With Alcoholic Liver Disease

Autor: Charles S. Lieber, Theresa M. Worner
Rok vydání: 1980
Předmět:
Zdroj: Alcoholism: Clinical and Experimental Research. 4:431-434
ISSN: 0145-6008
DOI: 10.1111/j.1530-0277.1980.tb04845.x
Popis: The time course of plasma glutamate dehydrogenase (GDH) elevation was studied in 42 male alcoholics admitted for alcohol detoxification or for the treatment of medical complications of alcoholism and in 2 volunteers consuming 2 g/kg/day of ethanol under metabolic ward conditions. GDH values were usually highest during or immediately after cessation of drinking; thereafter, they fell rapidly toward the normal range. Early GDH values correlated well with liver histology in 37 patients who subsequently underwent diagnostic liver biopsy.
Databáze: OpenAIRE