HTLV-I/II Seropositivity in Populations at High Risk for HIV-1 Infection in Cordoba City, Argentina
| Autor: | Miguel O. Giordano, Eduardo Maturano, Silvia Nates, Silvia Medeot, Yamile Recalde, Sandra Gallego, Raul Bocangel Alvarez, Santos Sileoni |
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| Rok vydání: | 1998 |
| Předmět: |
Blood transfusion
viruses medicine.medical_treatment Blotting Western Immunology Population Argentina Human immunodeficiency virus (HIV) HIV Infections medicine.disease_cause Risk Factors Seroepidemiologic Studies immune system diseases Agglutination Tests hemic and lymphatic diseases Virology HIV Seropositivity Prevalence medicine Humans Immunology and Allergy Htlv i ii Seroprevalence Fluorescent Antibody Technique Indirect education education.field_of_study biology business.industry virus diseases Serum samples HTLV-I Infections HTLV-I Antibodies HTLV-II Antibodies Agglutination (biology) HTLV-II Infections HIV-1 biology.protein Antibody business |
| Zdroj: | Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 18:187-188 |
| ISSN: | 1077-9450 |
| Popis: | Recent epidemiologic studies in Buenos Aires suggest the presence of HTLV-I/II in blood banks and in the population at risk for HIV-1 infection with seroprevalence of 4% among IV drug users 0.5% in homosexual men and 0.1% in blood donors. However neither blood nor blood derivatives in Argentina are screened for these agents. Findings are presented from an HTLV-I/II seroprevalence survey conducted in Cordoba City Argentina. 312 serum samples collected during 1985-95 from HIV-1-positive subjects and others exposed to HIV through blood transfusion were screened for antibodies to HTLV-I/II. Of 10 sera reactive to Serodia HTLV-I particulate agglutination (PA) assay 6 were confirmed HTLV-I-positive and 1 was confirmed HTLV-II-positive by indirect immunofluorescence assay (IFA). Of 6 HTLV-I-positive samples on IFA 5 were confirmed positive by Western blot (WB) but 1 sample was not tested. The IFA HTLV-II-positive sample was indeterminate with a weak reaction to the p24 and p19 HTLV-I proteins. Blood banks should screen for the presence of HTLV-I/II infection in blood supplies in order to prevent their widespread dissemination in the population. |
| Databáze: | OpenAIRE |
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