Association between Inflammatory Bowel Disease and Pancreatitis: A PRISMA-Compliant Systematic Review
| Autor: | Li Pengfan, Yan Xue, Kanjun Chen, Danbo Dou, Sizhen Gu, Lihang Zhang, Xueying Wang, Yue Luo, Zheng Mao, Yuli Zhang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Abdominal pain Hepatology business.industry Gastroenterology MEDLINE RC799-869 Review Article Diseases of the digestive system. Gastroenterology medicine.disease Inflammatory bowel disease 03 medical and health sciences 0302 clinical medicine Chronic diarrhea Weight loss 030220 oncology & carcinogenesis Internal medicine medicine Pancreatitis Acute pancreatitis 030211 gastroenterology & hepatology In patient medicine.symptom business |
| Zdroj: | Gastroenterology Research and Practice Gastroenterology Research and Practice, Vol 2020 (2020) |
| ISSN: | 1687-6121 |
| Popis: | Background/Objectives. This systematic review was conducted to investigate the association between pancreatitis and IBD. Methods. MEDLINE, Embase, and CENTRAL were systematically searched for correlative studies till 2 November 2019. RevMan5.3 was used to estimate relevance. Results. Three studies with 166008 participants were included. The risk of pancreatitis significantly increased in the patients with CD (OR, 3.40; 95% CI, 2.70-4.28; P<0.00001) and UC (OR, 2.49; 95% CI, 1.91-3.26; P<0.00001). Increased risks of CD (OR, 12.90; 95% CI, 5.15-32.50; P<0.00001) and UC (OR, 2.80; 95% CI, 1.00-7.86; P=0.05) were found in patients with chronic pancreatitis. As for patients with acute pancreatitis, there were significant association of CD (OR, 3.70; 95% CI, 1.90-7.60; P=0.0002), but were not UC. Conclusions. The evidence confirmed an association between pancreatitis and IBD. When pancreatitis patients have chronic diarrhea and mucus blood stool or IBD patients have repeated abdominal pain and weight loss, they should consult pancreatic and gastrointestinal specialists. |
| Databáze: | OpenAIRE |
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