Composition and properties of extract of fiddleback (Loxosceles reclusa) spider venom apparatus
| Autor: | D.E. Howell, Collis R. Geren, K. Pinkston, George V. Odell, Tak K. Chan, Billy C. Ward |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Spider
Erythrocytes Chromatography Venoms Isoelectric focusing Size-exclusion chromatography Molecular Conformation Spiders Venom Biology Electrophoresis Disc Toxicology Hemolysis Molecular Weight Column chromatography Disc gel electrophoresis Chromatography Gel Animals Composition (visual arts) Rabbits Isoelectric Focusing |
| Zdroj: | Toxicon. 11:471-479 |
| ISSN: | 0041-0101 |
| Popis: | A lethal extract of the venom of the fiddleback spider, Loxosceles reclusa , has been prepared. This extract was fractionated into several components, using gel filtration column chromatography and preparative disc gel electrophoresis techniques. Two of the isolated components are capable of producing lesions and death in test animals. The molecular weight of both components as determined by thin-layer gel filtration is approximately 24,000. The pI of both components as indicated by isoelectric focusing is 8·3. |
| Databáze: | OpenAIRE |
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