Carbamoyl Fluoride-Enabled Enantioselective Ni-Catalyzed Carbocarbamoylation of Unactivated Alkenes
| Autor: | Shao-Long Qi, Rong-Hua Wang, Mengchun Ye, Feng-Ping Zhang, Yu-Xin Luan, Yue Li |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Enantioselective synthesis General Chemistry 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry Catalysis 0104 chemical sciences chemistry.chemical_compound Colloid and Surface Chemistry chemistry Yield (chemistry) Fluoride |
| Zdroj: | Journal of the American Chemical Society. 142:19844-19849 |
| ISSN: | 1520-5126 0002-7863 |
| DOI: | 10.1021/jacs.0c09949 |
| Popis: | A carbamoyl fluoride-enabled enantioselective Ni-catalyzed carbocarbamoylation of unactivated alkenes was developed, providing a broad range of chiral γ-lactams bearing an all-carbon quaternary center in 45-96% yield and 38-97% ee. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|