Reactive Hyperemia-Triggered Wrist Pulse Analysis for Early Monitoring of Young Men with High Atherosclerotic Risk
| Autor: | Hsien-Tsai Wu, Jian-Jung Chen, Bagus Haryadi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Medicine (General) Waist business.industry Vascular disease cardiovascular disease (CVD) Clinical Biochemistry Disease medicine.disease dilation index (DI) Article Pulse pressure reactive hyperemia wrist pressure pulse (WPP) R5-920 Internal medicine Mann–Whitney U test Cardiology Medicine Heart rate variability Young adult business endothelial dysfunction (ED) Reactive hyperemia heart rate variability (HRV) |
| Zdroj: | Diagnostics Volume 11 Issue 10 Diagnostics, Vol 11, Iss 1918, p 1918 (2021) |
| ISSN: | 2075-4418 |
| DOI: | 10.3390/diagnostics11101918 |
| Popis: | The high prevalence of cardiovascular disease in young adults has raised significant concern regarding the early identification of risk factors to allow for timely intervention. This study aimed to identify young males at risk of atherosclerosis using a noninvasive instrument and an initial application percussion entropy analysis of the wrist pressure pulse (WPP). In total, 49 young males aged 18 to 28, without any known history of vascular disease, were recruited. Blood samples were obtained whereby a TC/HDL cutoff value of 4 was used to divide the young men into low-risk (Group 1, TC/HDL < 4, N = 32) and high-risk (Group 2, TC/HDL ≥ 4, N = 17) groups regarding atherosclerosis. The reactive hyperemia-triggered WPPs were measured using a modified air-pressure-sensing system (MAPSS). The dilation index (DI) of the endothelial function and percussion entropy index (PEI) of the heart rate variability (HRV) assessments, calculated using pragmatic signal-processing techniques, were compared between the two groups. The nonparametric Mann–Whitney U test showed that the DI and PEI of the two groups showed statistical differences (both p < 0.05). Not only could the MAPSS assess endothelial function and HRV in young males, but the results also showed that waist circumference and PEI may serve as indicators for the early identification of young males at risk of atherosclerosis. |
| Databáze: | OpenAIRE |
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