Seasonal changes in proteolytic activity of calpains in striated muscles of long-tailed ground squirrel Spermophilus undulatus
| Autor: | Zoya A. Podlubnaya, S. S. Popova, N. M. Zakharova, Ivan M. Vikhlyantsev, E. E. Fesenko |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Hibernation Biophysics Zoology Context (language use) Striated Muscles Biochemistry 03 medical and health sciences Spermophilus undulatus Animals Long-tailed ground squirrel Ground squirrel 030102 biochemistry & molecular biology Hyperactivation biology Calpain Sciuridae General Chemistry General Medicine Anatomy biology.organism_classification Muscle Striated 030104 developmental biology Proteolysis biology.protein Seasons sense organs psychological phenomena and processes |
| Zdroj: | Doklady Biochemistry and Biophysics. 472:56-59 |
| ISSN: | 1608-3091 1607-6729 |
| DOI: | 10.1134/s1607672917010148 |
| Popis: | Seasonal changes in proteolytic activity and content of calpains in striated muscles of the longtailed ground squirrel Spermophilus undulatus were studied by casein zymography and Western blotting analysis. The results testify to hyperactivation of calpain proteases in the skeletal muscles of awakened animals during the "winter" activity. The observed changes are discussed in the context of adaptation of skeletal muscles of long-tailed ground squirrels to hibernation. |
| Databáze: | OpenAIRE |
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