BLOCKAGE OF RESTRICTION ENDONUCLEASE CLEAVAGE BY THYMINE DIMERS

Autor:	L. L. Larcom, Robert K. Hall
Rok vydání:	1982
Předmět:	Base Sequence Pyrimidine dimer DNA Restriction Enzymes General Medicine Biology Cleavage (embryo) Biochemistry Molecular biology Kinetics Restriction enzyme Plasmid Pyrimidine Dimers DNA Viral Base sequence Physical and Theoretical Chemistry Dna viral
Zdroj:	Photochemistry and Photobiology. 36:429-432
ISSN:	1751-1097 0031-8655
DOI:	10.1111/j.1751-1097.1982.tb04398.x
Popis:	Viral DNAs were subjected to 254 nm irradiation and then digested with type II restriction endonucleases. At the fluences used, irradiation inhibited cleavage by nucleases which recognize sites containing neighboring thymines. Cleavage by endonucleases with other recognition sequences was not affected. In viral and plasmid DNAs, this effect could be used to study thymine dimer formation at a few specific, mapped sites of defined base sequence.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31db404f8fa927c9fae41dabbca08f3c https://doi.org/10.1111/j.1751-1097.1982.tb04398.x Zobrazit plný text záznamu Plný text