Type D personality is associated with increased prevalence of ventricular arrhythmias in community-residing persons without coronary heart disease
| Autor: | Gunnar Einvik, Virend K. Somers, Torbjørn Omland, Håvard Anton Kristiansen, Inger Hilde Nordhus, Toril Dammen, Silje K. Namtvedt, Anna Randby, Harald Hrubos-Strøm |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Epidemiology media_common.quotation_subject Disease Anxiety Personality Assessment Risk Assessment Type D Personality Risk Factors Internal medicine Heart rate Odds Ratio Prevalence medicine Humans Personality Heart rate variability Risk factor Aged media_common Chi-Square Distribution Norway business.industry Type D personality Middle Aged Ventricular Premature Complexes Coronary heart disease Cross-Sectional Studies Logistic Models Multivariate Analysis Electrocardiography Ambulatory Linear Models Tachycardia Ventricular Cardiology Female Independent Living medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | European Journal of Preventive Cardiology. 21:592-600 |
| ISSN: | 2047-4881 2047-4873 |
| Popis: | Type D personality may be a risk factor for poor outcome in patients with cardiovascular disease. The biological mechanisms underlying this association are poorly understood. The objective of the study was to test the hypotheses that Type D personality is associated with biological markers for sympathetic dysregulation.Cross-sectional community-based study.Type D personality was evaluated by DS-14 in 450 persons (46% men), aged between 30 and 65 years. From a Holter-recording, (mean length 18.3 hours), long-term heart rate, ventricular arrhythmias, and heart rate variability (HRV) were registered as markers of sympathetic dysregulation. Traditional cardiovascular risk factors, apnoea-hypopnoea index, medication, and anxiety symptoms were adjusted for.Type D persons had higher long-term averaged heart rate (74 vs. 71 beats/min, p = 0.003), but this difference was attenuated and not significant in the multivariate model (p = 0.078)). There was an increased prevalence of complex ventricular ectopy (bigeminy, trigeminy, or non-sustained ventricular tachycardia; 14 vs. 6%, p = 0.005 in multivariate model). HRV indices did not differ significantly between those with or without Type D personality. Anxiety symptoms did not confound these associations.Type D personality is independently associated with a higher likelihood of ventricular arrhythmias, which may be implicated in the increased cardiovascular risk observed in persons with Type D personality. |
| Databáze: | OpenAIRE |
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