Therapeutic Concentrations of Griseofulvin Do Not Affect Yeast Cell Phagocytosis by Monocytes

Autor:	Leif Athlin, Bo Norberg, L. Domellöf
Rok vydání:	1987
Předmět:	Adult Male Monocyte Phagocytosis Cell Adhesiveness Saccharomyces cerevisiae Dermatology In Vitro Techniques Middle Aged Biology Griseofulvin Monocytes Yeast Culture Media Microbiology chemistry.chemical_compound medicine.anatomical_structure chemistry medicine Humans Female Glass
Zdroj:	Dermatology. 174:122-127
ISSN:	1421-9832 1018-8665
DOI:	10.1159/000249002
Popis:	The effect of griseofulvin on monocyte phagocytosis was assessed by studying the uptake of fluorescent yeast cells by glass-adherent monocytes (a fluorescence-quenching technique). In contrast to other microtubule antagonists, grisofulvin did not inhibit monocyte phagocytosis. It is suggested that the lack of griseofulvin interference with essential leukocyte functions is a possible explanation for the fact that the microtubule antagonist griseofulvin serves as a comparatively safe and harmless drug.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d2561e8b3fb836ac2877ce168271fc https://doi.org/10.1159/000249002 Zobrazit plný text záznamu