Incidental breast lesions detected on CT: what is their significance?
| Autor: | L Sonoda, P D Britton, Penny Moyle, R. Sinnatamby |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Mammary gland Contrast Media Enhancement pattern Breast Neoplasms Malignancy Breast Neoplasms Male Lesion Breast cancer medicine Humans Radiology Nuclear Medicine and imaging skin and connective tissue diseases Aged Retrospective Studies Aged 80 and over Incidental Findings Full Paper business.industry Retrospective cohort study General Medicine Middle Aged medicine.disease Predictive value Iopamidol medicine.anatomical_structure Female Radiology medicine.symptom business Tomography X-Ray Computed Calcification |
| Popis: | An increasing number of breast lesions are being detected incidentally on CT. The aim of this study was to investigate the rate of referrals to the breast unit for assessment of lesions identified on CT and the resulting yield of previously undiagnosed breast malignancies from this pathway. A retrospective review was undertaken of CT examinations conducted over a period of 14 years. All patients (with no previous history of breast cancer) whose report contained the keyword "breast" and who were referred to a specialist breast unit for assessment were reviewed. CT lesion morphology and enhancement pattern were identified and compared with the final diagnostic outcome. 70 patients were identified by retrospective analysis, yielding 78 incidental breast lesions, of which 22 (28.2%) were malignant (category B5). This gave a positive predictive value (PPV) for malignancy of 28.2%. The best morphological predictor of malignancy was spiculation (PPV, 76%) and irregularity (PPV, 58%), whereas calcification patterns (PPV, 36%) were diagnostically unhelpful. Malignant lesions were likely to be larger (mean, 28.5 mm) than benign lesions (mean, 20.2 mm; p |
| Databáze: | OpenAIRE |
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