The Relationship Between Sickle Cell Disease and Sudden Onset Sensorineural Deafness
| Autor: | Elabbass Abdelmahmuod, Mohamed A. Yassin, Mohanad Mohsin Ahmed, Elrazi Ali |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Hearing loss Disease 030204 cardiovascular system & hematology Vascular occlusion Gastroenterology scd sensorineural hearing loss 03 medical and health sciences 0302 clinical medicine sickle cell anemia Internal medicine deafness medicine Internal Medicine Molecular lesion Genitourinary system business.industry Incidence (epidemiology) General Engineering Endocrinology/Diabetes/Metabolism hemoglobin sickle cell medicine.disease Sickle cell anemia Nephrology Sensorineural hearing loss sickle cell disease medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Sickle cell anemia (SCA) is a hereditary hemoglobin (Hb) disorder associated with a very specific molecular lesion, which is the exchange of glutamic acid for valine in the sixth residue of the Hb beta chain, originating the S Hb. It is characterized by intermittent episodes of vascular occlusion and end-organ damage. Progressive organ damage may affect any organ with brain, eyes, pulmonary, hepatobiliary, spleen, genitourinary, and the musculoskeletal systems being the most commonly involved and reported. Other complications of the disease that have not been well described or studied include cranio-orbital syndromes, oropharyngeal syndromes, periodontal disease, and otologic syndromes. Considering the vaso-occlusive nature of sickle cell disease (SCD), the potential for auditory damage is not unexpected. However, the incidence of subjective hearing impairment among SCA is very low and and little is known about the relationship between SCA and hearing loss. Here we report a 43-year-old female with SCA who presented with sudden bilateral hearing loss and generalized body ache and admitted as a case of sensorineural deafness with vascular crisis; she received IV fluid and analgesia and improved after five days from the therapy. |
| Databáze: | OpenAIRE |
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